Autologous stem cell therapy for peripheral arterial disease: meta-analysis and systematic review of the literature

GP Fadini, C Agostini, A Avogaro - Atherosclerosis, 2010 - Elsevier
BACKGROUND: Peripheral arterial disease (PAD) is a common cause of disability and
mortality. Up to one third of patients are not susceptible to traditional revascularization and
may benefit from stem cell therapies. OBJECTIVE: In this meta-analysis, we sought to
determine whether autologous cell therapy is effective in the treatment of PAD. METHODS:
We searched the English literature in Medline, Excerpta Medica and the Cochrane database
for trials of autologous cell therapy in patients with PAD published before 31 January 2009 …